Dr. Netoff's research laboratory focuses on understanding the basic neuroscience underlying epilepsy and developing new ways to treat epilepsy. Using mathematic analysis to simplify the non-linear and high order activity of the brain into meaningful and more easily understood data. Using the mathematical models they develop, can predict how new drugs will affect brain activity or how deep brain stimulation will alter synchrony in networks. Their goal is to develop new, innovative ways to predict, treat, and terminate seizures to improve patient care. His lab wants to better understand how seizures are generated and how they propagate through the brain. Their research leads to the belief that inhibitory cells may play a significant role in the onset of seizures.