The MnDRIVE Brain Conditions program supports three Non-invasive Neuromodulation Laboratories (NNL), created to facilitate non-invasive brain stimulation research at the University of Minnesota (UMN). The NNL aims to provide state-of-the-art technology for clinical trials using neuromodulation to better the understanding of psychiatric and neurological conditions, and to translate experimental findings to clinical practice for improved treatment methods and patient outcomes.
The primary Non-invasive Neuromodulation Laboratory is for adult participants and has a space of 315 square feet for experiments and consenting paperwork, located in the Delaware Clinical Research Unit within the 717 Delaware Building.
What is non-invasive neuromodulation?
Non-invasive neuromodulation refers to techniques that modulate (or influence) nervous system activity without the need for surgery or implanting devices inside the body. These methods use external devices to deliver stimuli—typically electrical or magnetic—to targeted areas of the brain, spinal cord, or peripheral nerves.
Common types of non-invasive neuromodulation include:
Transcranial Magnetic Stimulation (TMS): Uses magnetic fields to stimulate nerve cells in the brain, often used for depression and other psychiatric or neurological conditions.
Transcranial Direct Current Stimulation (tDCS): Applies a low electrical current through electrodes placed on the scalp to modulate brain activity.
Transcutaneous Electrical Nerve Stimulation (TENS): Delivers electrical pulses to peripheral nerves via skin electrodes, commonly used for pain management.
Transcutaneous Vagus Nerve Stimulation (tVNS): Stimulates the vagus nerve through the skin, usually near the ear or neck, for conditions like epilepsy and depression.
These techniques are generally safer and more accessible than invasive methods, though they may offer more modest or temporary effects depending on the condition being treated.
