Patrick Rothwell, Ph.D.

Neuromodulation Scholar, Assistant Professor — Neuroscience

 

Patrick Rothwell Bio

Rothwell Lab

Current Publications

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Current Publications

2024

1. Singh, R., Jiang, R., Williams, J., Dobariya, P., Hanak, F., Xie, J., Rothwell, P. E., Vince, R., & More, S. S. (2024). Modulation of endogenous opioid signaling by inhibitors of puromycin sensitive aminopeptidase. bioRxiv : the preprint server for biology, 2024.04.02.587756. https://doi.org/10.1101/2024.04.02.587756

2023

1. Lefevre, E. M., Gauthier, E. A., Bystrom, L. L., Scheunemann, J., & Rothwell, P. E. (2023). Differential Patterns of Synaptic Plasticity in the Nucleus Accumbens Caused by Continuous and Interrupted Morphine Exposure. Journal of Neuroscience, 43(2), 308-318. https://doi.org/10.1523/JNEUROSCI.0595-22.2022

2. Brandner, D. D., Retzlaff, C. L., Kocharian, A., Stieve, B. J., Mashal, M. A., Mermelstein, P. G., & Rothwell, P. E. (2023). Neuroligin-3 in dopaminergic circuits promotes behavioural and neurobiological adaptations to chronic morphine exposure. Addiction Biology, 28(1), Article e13247. https://doi.org/10.1111/adb.13247

2022

1. Retzlaff, C. L., & Rothwell, P. E. (2022). Characterization and mu opioid receptor sensitivity of neuropeptide Y interneurons in the mouse nucleus accumbens. Neuropharmacology, 218, [109212]. https://doi.org/10.1016/j.neuropharm.2022.109212

2. Trieu, B. H., Remmers, B. C., Toddes, C., Brandner, D. D., Lefevre, E. M., Kocharian, A., Retzlaff, C. L., Dick, R. M., Mashal, M. A., Gauthier, E. A., Xie, W., Zhang, Y., More, S. S., & Rothwell, P. E. (2022). Angiotensin-converting enzyme gates brain circuit–specific plasticity via an endogenous opioid. Science, 375(6585), 1177-1182. https://doi.org/10.1126/science.abl5130

2021

1. Toddes, C., Lefevre, E. M., Brandner, D. D., Zugschwert, L., & Rothwell, P. E. (2021). μ-opioid receptor (oprm1) copy number influences nucleus accumbens microcircuitry and reciprocal social behaviors. Journal of Neuroscience, 41(38), 7965-7977. https://doi.org/10.1523/jneurosci.2440-20.2021

2020

1. Borland, J. M., Kim, E., Swanson, S. P., Rothwell, P. E., Mermelstein, P. G., & Meisel, R. L. (2020). Effect of Aggressive Experience in Female Syrian Hamsters on Glutamate Receptor Expression in the Nucleus Accumbens. Frontiers in Behavioral Neuroscience, 14, Article 583395. https://doi.org/10.3389/fnbeh.2020.583395

2. Lefevre, E. M., Pisansky, M. T., Toddes, C., Baruffaldi, F., Pravetoni, M., Tian, L., Kono, T. J. Y., & Rothwell, P. E. (2020). Interruption of continuous opioid exposure exacerbates drug-evoked adaptations in the mesolimbic dopamine system. Neuropsychopharmacology, 45(11), 1781-1792. https://doi.org/10.1038/s41386-020-0643-x

3. Corkrum, M., Covelo, A., Lines, J., Bellocchio, L., Pisansky, M., Loke, K., Quintana, R., Rothwell, P. E., Lujan, R., Marsicano, G., Martin, E. D., Thomas, M. J., Kofuji, P., & Araque, A. (2020). Dopamine-Evoked Synaptic Regulation in the Nucleus Accumbens Requires Astrocyte Activity. Neuron, 105(6), 1036-1047.e5. https://doi.org/10.1016/j.neuron.2019.12.026

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Patrick Rothwell