Alexander Opitz, Ph.D.

Neuromodulation Scholar, Assistant Professor — Biomedical Engineering

 

Alexander Opitz Bio

Opitz Lab

Current Publications

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Current Publications

2024

1. Wischnewski, M., Berger, T. A., Opitz, A., & Alekseichuk, I. (2024). Causal functional maps of brain rhythms in working memory. Proceedings of the National Academy of Sciences of the United States of America, 121(14), e2318528121. https://doi.org/10.1073/pnas.2318528121

2. Wischnewski, M., Tran, H., Zhao, Z., Shirinpour, S., Haigh, Z. J., Rotteveel, J., Perera, N. D., Alekseichuk, I., Zimmermann, J., & Opitz, A. (2024). Induced neural phase precession through exogenous electric fields. Nature communications, 15(1), 1687. https://doi.org/10.1038/s41467-024-45898-5

3. Zhao, Z., Shirinpour, S., Tran, H., Wischnewski, M., & Opitz, A. (2024). intensity- and frequency-specific effects of transcranial alternating current stimulation are explained by network dynamics. Journal of neural engineering, 21(2), 10.1088/1741-2552/ad37d9. https://doi.org/10.1088/1741-2552/ad37d9

4. Croarkin, P. E., & Opitz, A. (2024). Advances in precision neuromodulation: electroconvulsive therapy amplitude titration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 49(4), 635–636. https://doi.org/10.1038/s41386-024-01797-3

2023

1. Wischnewski, M., Alekseichuk, I., & Opitz, A. (2023). Neurocognitive, physiological, and biophysical effects of transcranial alternating current stimulation. Trends in cognitive sciences, 27(2), 189–205. https://doi.org/10.1016/j.tics.2022.11.013

2. Mantell, K. E., Perera, N. D., Shirinpour, S., Puonti, O., Xu, T., Zimmermann, J., Falchier, A., Heilbronner, S. R., Thielscher, A., & Opitz, A. (2023). Anatomical details affect electric field predictions for non-invasive brain stimulation in non-human primates. NeuroImage, 279, 120343. https://doi.org/10.1016/j.neuroimage.2023.120343

3. Conelea, C., Greene, D. J., Alexander, J., Houlihan, K., Hodapp, S., Wellen, B., Francis, S., Mueller, B., Hendrickson, T., Tseng, A., Chen, M., Fiecas, M., Lim, K., Opitz, A., & Jacob, S. (2023). The CBIT + TMS trial: study protocol for a two-phase randomized controlled trial testing neuromodulation to augment behavior therapy for youth with chronic tics. Trials, 24(1), 439. https://doi.org/10.1186/s13063-023-07455-1

4. Perera, N. D., Alekseichuk, I., Shirinpour, S., Wischnewski, M., Linn, G., Masiello, K., Butler, B., Russ, B. E., Schroeder, C. E., Falchier, A., & Opitz, A. (2023). Dissociation of Centrally and Peripherally Induced Transcranial Magnetic Stimulation Effects in Nonhuman Primates. The Journal of neuroscience : the official journal of the Society for Neuroscience, 43(50), 8649–8662. https://doi.org/10.1523/JNEUROSCI.1016-23.2023

5. Soleimani, G., Kuplicki, R., Camchong, J., Opitz, A., Paulus, M. P., Lim, K. O., & Ekhtiari, H. (2023). Are we really targeting and stimulating DLPFC by placing transcranial electrical stimulation (tES) electrodes over F3/F4?. Human brain mapping, 44(17), 6275–6287. https://doi.org/10.1002/hbm.26492

6. Soleimani, G., Conelea, C. A., Kuplicki, R., Opitz, A., Lim, K. O., Paulus, M. P., & Ekhtiari, H. (2023). Optimizing Individual Targeting of Fronto-Amygdala Network with Transcranial Magnetic Stimulation (TMS): Biophysical, Physiological and Behavioral Variations in People with Methamphetamine Use Disorder. medRxiv : the preprint server for health sciences, 2023.04.02.23288047. https://doi.org/10.1101/2023.04.02.23288047

7. Lee, S., Shirinpour, S., Alekseichuk, I., Perera, N., Linn, G., Schroeder, C. E., Falchier, A. Y., & Opitz, A. (2023). Predicting the phase distribution during multi-channel transcranial alternating current stimulation in silico and in vivo. Computers in biology and medicine, 166, 107516. https://doi.org/10.1016/j.compbiomed.2023.107516

2022

1. Wischnewski, M., Haigh, Z. J., Shirinpour, S., Alekseichuk, I., & Opitz, A. (2022). The phase of sensorimotor mu and beta oscillations has the opposite effect on corticospinal excitability. Brain stimulation, 15(5), 1093–1100. https://doi.org/10.1016/j.brs.2022.08.005

2. Alekseichuk, I., Wischnewski, M., & Opitz, A. (2022). A minimum effective dose for (transcranial) alternating current stimulation. Brain stimulation, 15(5), 1221–1222. https://doi.org/10.1016/j.brs.2022.08.018

3. Turi, Z., Hananeia, N., Shirinpour, S., Opitz, A., Jedlicka, P., & Vlachos, A. (2022). Dosing Transcranial Magnetic Stimulation of the Primary Motor and Dorsolateral Prefrontal Cortices With Multi-Scale Modeling. Frontiers in neuroscience, 16, 929814. https://doi.org/10.3389/fnins.2022.929814

4. Ekhtiari, H., Ghobadi-Azbari, P., Thielscher, A., Antal, A., Li, L. M., Shereen, A. D., Cabral-Calderin, Y., Keeser, D., Bergmann, T. O., Jamil, A., Violante, I. R., Almeida, J., Meinzer, M., Siebner, H. R., Woods, A. J., Stagg, C. J., Abend, R., Antonenko, D., Auer, T., Bächinger, M., … Bikson, M. (2022). A checklist for assessing the methodological quality of concurrent tES-fMRI studies (ContES checklist): a consensus study and statement. Nature protocols, 17(3), 596–617. https://doi.org/10.1038/s41596-021-00664-5

5. Tran, H., Shirinpour, S., & Opitz, A. (2022). Effects of transcranial alternating current stimulation on spiking activity in computational models of single neocortical neurons. NeuroImage, 250, 118953. https://doi.org/10.1016/j.neuroimage.2022.118953

2021

1. Wischnewski, M., Mantell, K. E., & Opitz, A. (2021). Identifying regions in prefrontal cortex related to working memory improvement: A novel meta-analytic method using electric field modeling. Neuroscience and biobehavioral reviews, 130, 147–161. https://doi.org/10.1016/j.neubiorev.2021.08.017

2. Shirinpour, S., Hananeia, N., Rosado, J., Tran, H., Galanis, C., Vlachos, A., Jedlicka, P., Queisser, G., & Opitz, A. (2021). Multi-scale modeling toolbox for single neuron and subcellular activity under Transcranial Magnetic Stimulation. Brain stimulation, 14(6), 1470–1482. https://doi.org/10.1016/j.brs.2021.09.004

3. Mantell, K. E., Sutter, E. N., Shirinpour, S., Nemanich, S. T., Lench, D. H., Gillick, B. T., & Opitz, A. (2021). Evaluating transcranial magnetic stimulation (TMS) induced electric fields in pediatric stroke. NeuroImage. Clinical, 29, 102563. https://doi.org/10.1016/j.nicl.2021.102563

2020

1. Boayue, N. M., Csifcsák, G., Aslaksen, P., Turi, Z., Antal, A., Groot, J., Hawkins, G. E., Forstmann, B., Opitz, A., Thielscher, A., & Mittner, M. (2020). Increasing propensity to mind-wander by transcranial direct current stimulation? A registered report. The European journal of neuroscience, 51(3), 755–780. https://doi.org/10.1111/ejn.14347

2. Shirinpour, S., Alekseichuk, I., Mantell, K., & Opitz, A. (2020). Experimental evaluation of methods for real-time EEG phase-specific transcranial magnetic stimulation. Journal of neural engineering, 17(4), 046002. https://doi.org/10.1088/1741-2552/ab9dba

3. Johnson, L., Alekseichuk, I., Krieg, J., Doyle, A., Yu, Y., Vitek, J., Johnson, M., & Opitz, A. (2020). Dose-dependent effects of transcranial alternating current stimulation on spike timing in awake nonhuman primates. Science advances, 6(36), eaaz2747. https://doi.org/10.1126/sciadv.aaz2747

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Alexander Opitz