Department of Neuroscience
Mentor: Matthew Johnson, Ph.D., Department of Biomedical Engineering
Project: Deep Brain Stimulation for Obsessive-Compulsive Disorder: Identifying Pathway Activation Patterns for Improving Cognitive Control
Karianne Sretavan Wong’s research aims to identify how deep brain stimulation (DBS) parameters and white matter pathway activation in the ventral anterior limb of the internal capsule results in cognitive control improvements for patients with severe obsessive-compulsive disorder (OCD). This project’s findings will be the first to translate the use of patient-specific computational models into the psychiatric space for OCD patients to inform clinicians about which white matter pathways to target and how to optimize stimulation settings for cognitive control improvements.